3D Printable Device for Automated Operant Conditioning in the Mouse
Por um escritor misterioso
Last updated 05 julho 2024
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://www.eneuro.org/content/7/2/ENEURO.0502-19.2020/F1.large.jpg)
Operant conditioning (OC) is a classical paradigm and a standard technique used in experimental psychology in which animals learn to perform an action to achieve a reward. By using this paradigm, it is possible to extract learning curves and measure accurately reaction times (RTs). Both these measurements are proxy of cognitive capabilities and can be used to evaluate the effectiveness of therapeutic interventions in mouse models of disease. Here, we describe a fully 3D printable device that is able to perform OC on freely moving mice, while performing real-time tracking of the animal position. We successfully trained six mice, showing stereotyped learning curves that are highly reproducible across mice and reaching >70% of accuracy after 2 d of conditioning. Different products for OC are commercially available, though most of them do not provide customizable features and are relatively expensive. This data demonstrate that this system is a valuable alternative to available state-of-the-art commercial devices, representing a good balance between performance, cost, and versatility in its use.
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://edspace.american.edu/openbehavior/wp-content/uploads/sites/1502/2020/05/ToneBox-1.jpg)
ToneBox: a system for automated auditory operant conditioning - OpenBehavior
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://iiif.elifesciences.org/lax/66173%2Felife-66173-fig3-v2.tif/full/,1500/0/default.jpg)
An open-source device for measuring food intake and operant behavior in rodent home-cages
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://www.jove.com/files/ftp_upload/59784/59784fig3large.jpg)
Evaluating Skilled Prehension in Mice Using an Auto-Trainer
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://edspace.american.edu/openbehavior/wp-content/uploads/sites/1502/2021/04/captouch-1080x427.jpg)
3D print Archives - Page 2 of 8 - OpenBehavior
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-021-01717-1/MediaObjects/41598_2021_1717_Fig2_HTML.png)
A low-cost open-source 5-choice operant box system optimized for electrophysiology and optophysiology in mice
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://www.frontiersin.org/files/Articles/346129/fnsys-12-00018-HTML/image_m/fnsys-12-00018-g001.jpg)
Frontiers Open Source Tools for Temporally Controlled Rodent Behavior Suitable for Electrophysiology and Optogenetic Manipulations
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://www.eneuro.org/content/eneuro/7/2/ENEURO.0502-19.2020/F3.large.jpg)
3D Printable Device for Automated Operant Conditioning in the Mouse
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://www.researchgate.net/publication/337976310/figure/fig2/AS:837088115163136@1576588767112/Schematic-representation-of-the-odor-port-and-the-olfactometer-A-Cross-section-view.png)
Schematic representation of the odor port and the olfactometer. (A)
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://edspace.american.edu/openbehavior/wp-content/uploads/sites/1502/2020/04/AutonoMouse-1.jpg)
AutonoMouse - OpenBehavior
![3D Printable Device for Automated Operant Conditioning in the Mouse](https://open-neuroscience.com/post/neurotwin/featured_hud109d9c66059217af2bab44795aa78ad_73385_550x0_resize_lanczos_2.png)
Open Neuroscience
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